Correction of Spatial Bias in Oligonucleotide Array Data
نویسندگان
چکیده
منابع مشابه
Correction of Spatial Bias in Oligonucleotide Array Data
Background. Oligonucleotide microarrays allow for high-throughput gene expression profiling assays. The technology relies on the fundamental assumption that observed hybridization signal intensities (HSIs) for each intended target, on average, correlate with their target's true concentration in the sample. However, systematic, nonbiological variation from several sources undermines this hypothe...
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ژورنال
عنوان ژورنال: Advances in Bioinformatics
سال: 2013
ISSN: 1687-8027,1687-8035
DOI: 10.1155/2013/167915